At a high-traffic intersection on the south side of St. Louis, in a former bank building complete with a glassy atrium, it’s time for sewing class — held in Dari, the Afghan variant of Persian.

The walls are hung with photos of Afghanistan, from which most of the students have recently arrived. Before class starts, a handful of women in sneakers and head scarves first go to another room for prayer, while their younger children scamper around a well-equipped play room. They return to dated sewing machines, learning how to run tiny businesses from their homes as they acclimate to their new country.

The two-year-old Afghan Community Center has been an anchor for Halima Osmani, 20, who arrived from Afghanistan last summer with her parents and seven siblings. She now runs her own tailoring business, selling to local women through an Instagram account, while she works on getting her G.E.D. Eventually, she wants to become a physician assistant, and St. Louis seems like a good place to fulfill her dreams.

“Our first choice was Virginia,9x999 but we ended up here and liked it,” Ms. Osmani said through a translator; she is still learning English. “The first thing we noticed here was that it wasn’t crowded.”

Not being crowded — that’s both a problem and an opportunity for the grand but diminished city, which has been losing population for decades. The city’s politicians, business community, religious institutions and philanthropists have embraced a push to reverse that trend through immigration. In addition to refugees like Ms. Osmani, they’re trying to attract people from Central and South America, as well as international students and highly skilled professionals on employment visas.

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But the truth is that Mr. Biden will speak at a time of deep uncertainty about the future of America’s role in the world, including the war in Ukraine, escalating conflicts in the Middle East and growing economic competition with China.

Over the years, Ms. Judd told her son extremely little about her missing husband, who remained unaccounted for until May of this year. The Defense Department said earlier this month that her husband, Staff Sgt. John A. Tarbert of the Air Force was killed at 24 after his plane was attacked while flying over Germany 80 years ago this Friday.

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